Laboratory for Chemistry and Life Science, Institute of Integrated Research, Institute of Science Tokyo

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  • 2026.06.15

Genetic engineering of cyanobacteria for the production of sulfated polysaccharide

Genetically engineered cyanobacteria developed at Institute of Science Tokyo (Science Tokyo), Japan, produce sulfated polysaccharides using sunlight and carbon dioxide. By transferring an entire gene cluster responsible for the production of a sulfated polysaccharide, the researchers enabled a non-producing cyanobacterial strain to produce such a polysaccharide. The research demonstrates a sustainable route for manufacturing biomaterials using photosynthesis, expanding the possibilities for synthetic biology and green chemistry applications.

Reference

●Authors Kaisei Maeda1, Kazuma Ohdate2, Yutaka Sakamaki2, Kaori Nimura-Matsune2, and Satoru Watanabe2
●Title Transfer of the synechan biosynthesis and regulatory pathway enables sulfated polysaccharide production in Synechococcus elongatus PCC 7942
●Journal Scientific Reports
●First published:April 28, 2026
●DOI 10.1038/s41598-026-46439-4

Related information

Tanaka-Yoshida Group
Department of Life Science and Technology, School of Life Science and Technology
■Science Tokyo News:Genetic engineering of cyanobacteria for the production of sulfated polysaccharide

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